A 27-year-old healthy, Caucasian woman was referred to the dermatology clinic with a 1.5×1.5cm uniformly, hyperpigmented, light brown patch with irregular borders on her right palmar hand (Fig. 1A) that has been increasing in size for approximately one year. The patient did not endorse any scaling, blistering, or bleeding from the lesion. Furthermore, the patient did not report any itching, pain, and burning from the involved area. No prescribed or over-the-counter treatments were used prior to presentation.