Augmentation index is reduced in patients with inflammatory bowel disease, a meta-analysis

Published: 22 December 2016
Author(s): Luca Zanoli, Antonio Granata, Paolo Lentini, Agostino Gaudio, Pietro Castellino
Section: Letters to the Editor

In a work published in a recent issue of the European Journal of Internal Medicine [1], Cappello et al. found that, despite the lower prevalence of dyslipidemia, carotid-femoral pulse wave velocity, a measure of arterial stiffness, and augmentation index, a measure of wave reflection, were significantly increased in patients with inflammatory bowel disease (IBD), a disease characterized by chronic inflammation. This finding confirms the results of our previous works [2,3] and is of clinical interest because it helps explain why IBD patients have an increased cardiovascular risk despite the low prevalence of traditional cardiovascular risk factors [4].