Published: 16 December 2017
Author(s): Gaetano Bergamaschi, Michela Masotti, Gino Roberto Corazza
Section: Letter to the Editor

Serum creatinine and estimated glomerular filtration rate (eGFR), determined using the Modification of Diet Renal Disease (MDRD)-4, the MDRD-6 or the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equations, substantially overestimate kidney function in patients with liver cirrhosis [1]. By directly measuring GFR, Kalafateli et al. developed an alternative eGFR formula, the Royal Free Hospital (RFH) cirrhosis GFR, that more accurately estimates GFR in cirrhotic patients [2]. The tight correlation between measured GFR and RFH cirrhosis GFR was later confirmed by Pedersen et al.

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The principal objectives of EFIM is to promote internal medicine on a scientific educational, ethical and professional level and to support internists in providing better care for patients throughout Europe.

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The specialty of internal medicine covers a wide range of conditions affecting the internal organs of the body. Although some diseases specifically affect individual organs, the majority of common diseases. The internist must then be trained to recognise and manage a broad range of diseases and, with the aging population, many patients with chronic and multiple disorders.

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