Association of troponin levels below the 99th percentile with outcomes in patients with acute chest pain

Published: 7 January 2016
Author(s): Alberto Bouzas-Mosquera, Jesús Peteiro, Ignacio Pedro Constanso, Nemesio Álvarez-García, José Manuel Vázquez-Rodríguez
Issue: January 2016
Section: Letters to the Editor

We thank Drs. Lippi and Cervellin for their interest in our report [1] and for their thoughtful comments [2]. We agree that patients with suspected acute coronary syndromes and serial cardiac troponin levels below the 99th percentile of a healthy normal population have a lower risk of subsequent cardiac events. Nonetheless, the results of our study are consistent with previous observations in this subset of patients suggesting that this risk increases gradually from the limit of detection of the assay [3].