Utility of NT-proBNP in predicting infarct scar and left ventricular dysfunction at a chronic stage after myocardial infarction

Published: 8 January 2016
Author(s): Sebastian Johannes Reinstadler, Hans-Josef Feistritzer, Martin Reindl, Gert Klug, Bernhard Metzler
Issue: January 2016
Section: Letters to the Editor

Infarct healing is a dynamic process, characterized by a marked reduction of infarct size within the first months, followed by a more gradual reduction through the first year after STEMI [1]. CMR imaging is the reference method for the visualization of myocardial damage and cardiac function in vivo [2]. N-terminal pro B-type natriuretic peptide (NT-proBNP) is a cardiac neurohormone with prognostic value in patients with reperfused ST-elevation myocardial infarction (STEMI) [3]. NT-proBNP concentrations, measured during the acute phase after STEMI, are correlated with acute and chronic infarct size as well as left ventricular (LV) dysfunction as determined by cardiac magnetic resonance (CMR) imaging [4–6].