Multimorbidity and frailty are highly prevalent and emerging conditions [1–5]. Contrary to patients' and primary care providers' perceptions [6], multimorbidity does not necessarily imply the onset of frailty. However, both these conditions are determined by a wide and dynamic spectrum of potential causes [5,7,8] and they share several common aspects. For example, chronic diseases represent a key component of the frailty vicious cycle [9], and both conditions are associated with increased risk of negative outcomes for the individual as well as higher healthcare costs for public health [4,5].
