This 22years old woman was admitted for left upper lung pneumonia. She denied any systemic disease and never smoked. After antibiotic with ceftriaxone 2g per-day intravenous injection, the clinical symptoms, such as fever, cough subsided. Chest x ray revealed gradually resolution of pneumonia patch. However, her tongue became black [Fig. 1a] after 5days ceftriaxone use. Even she cleaned her tongue base with toothbrush and mouthwash regularly, but the tongue color was still dark. We collected culture from tongue and yield candida dubliniensis [Fig.