Published: 16 July 2019
Author(s): Vittorio Bertele', Rita Banzi, Chiara Gerardi, Silvio Garattini
Issue: July 2019
Section: Letter to the Editor

Testing new interventions against placebo when effective treatments are already available is considered unethical [1] and dangerous for patients [2], so testing non-inferiority which aims at demonstrating that a new intervention is not unacceptably worse than standard clinical practice should be equally unethical [3,4]. The understanding is that part of the benefit can be given up in exchange for less important advantages – such as better tolerability, convenience, etc. – which are claimed though often not proved.

Relevant EFIM Publications

The challenge of implementing Less is More medicine: A European perspective

Author(s): Omar Kherad, Nathan Peiffer-Smadja, Lina Karlafti, Margus Lember, Nathalie Van Aerde, Orvar Gunnarsson, Cristian Baicus, Miguel Bigotte Vieira, António Vaz-Carneiro, Antonio Brucato, Ivica Lazurova, Wiktoria Leśniak, Thomas Hanslik, Stephen Hewitt, Eleni Papanicolaou, Olga Boeva, Dror Dicker, Biljana Ivanovska, Pinar Yldiz, Patrick Lacor, Mark Cranston, Frauke Weidanz, Giorgio Costantino, Nicola Montano
Date:16 April 2020

Medical and surgical co-management – A strategy of improving the quality and outcomes of perioperative care

Author(s): Carmen Fierbinţeanu-Braticevicia, Matthias Raspeb, Alin Liviu Predac, Evija Livčāned, Leonid Lazebnike, Soňa Kiňováf, Evert- Jan de Kruijfg, Radovan Hojsh, Thomas Hansliki, Mine Durusu-Tanrioverj, Francesco Dentalik, Xavier Corbellal, Pietro Castellinom, Monica Bivoln, Stefano Bassettio, Vasco Barretop, Eduardo Montero Ruizq, Luis Camposr, The Working Group on Professional Issues and Quality of Care of the European Federation of Internal Medicine (EFIM)
Date:15 November 2018

Hospital ambulatory medicine: A leading strategy for Internal Medicine in Europe

Author(s): Xavier Corbellaa, Vasco Barretob, Stefano Bassettic, Monica Bivold, Pietro Castellinoe, Evert-Jan de Kruijff, Francesco Dentalig, Mine Durusu-Tanriöverh, Carmen Fierbinţeanu-Braticevicii, Thomas Hanslikj, Radovan Hojsk, Soňa Kiňovál, Leonid Lazebnikm, Evija Livčānen, Matthias Raspeo, Luis Camposp, The Working Group on Professional Issues and Quality of Care, European Federation of Internal Medicine (EFIM)
Date:14 April 2018


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What is EFIM?

The principal objectives of EFIM is to promote internal medicine on a scientific educational, ethical and professional level and to support internists in providing better care for patients throughout Europe.

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What is internal medicine?

The specialty of internal medicine covers a wide range of conditions affecting the internal organs of the body. Although some diseases specifically affect individual organs, the majority of common diseases. The internist must then be trained to recognise and manage a broad range of diseases and, with the aging population, many patients with chronic and multiple disorders.

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