Large databases (Big Data) and evidence-based medicine

Published: 25 May 2018
Author(s): Andrea Damiani, Graziano Onder, Vincenzo Valentini
Issue: June 2018
Section: Editorial

Evidence-based medicine (EBM) is more than 30 years old and has led to enormous changes in medical approaches through the development of increasingly objective guidelines, based on the results of randomized clinical trials (RCTs) and meta-analyses [1]. However, there are several concerns with the type of evidence that RCTs and meta-analyses provide.