Cholesterol absorption and synthesis markers in Portuguese hypercholesterolemic adults: A cross-sectional study

Published: 11 November 2015
Author(s): Isabel Andrade, Lèlita Santos, Fernando Ramos
Section: Original Article

The dynamics of cholesterol homeostasis and the development of cardiovascular disease (CVD) are complex and multifactorial, to which adds individual variability in the proportion of cholesterol from exogenous versus endogenous sources. The aim of this study was to undertake the first characterization of cholesterol absorption and synthesis profiles in Portuguese hypercholesterolemic adults through the quantification of surrogate markers, and the analysis of the predictive value of age and sex on the cholesterol homeostasis biomarkers.