Mild water restriction with or without urea for the longterm treatment of SIADH: Can urine osmolality help the choice?

Published: 7 October 2017
Author(s): G. Decaux, F. Gankam Kengne, B. Couturier, W. Musch, A. Soupart, F. Vandergheynst
Issue: October 2017
Section: Original Article

Treatment options for chronic SIADH include water restriction (WR) and urea. The usefulness of urine osmolality to guide the choice of the treatment option is not clearly defined. We hypothesized that urine osmolality can indicate whether treatment with mild water restriction alone could be successful.