Acute effect of dark chocolate on red blood cell distribution width

Published: 30 September 2016
Author(s): Martina Montagnana, Elisa Danese, Valentina Montolli, Gian Luca Salvagno, Giuseppe Lippi
Section: Letters to the Editor

Evidence accumulated over the past decades attests that moderate consumption of chocolate, especially dark chocolate, may produce favorable effects against cardiovascular disease [1]. Since anisocytosis, conventionally reflected by the amplitude of the red blood cell (RBC) distribution width (RDW), is increasingly regarded as a reliable marker and predictor of many cardiovascular disorders [2], we planned an original study to assess the impact of acute intake of dark chocolate on RDW.