Published: 11 October 2021
Author(s): Emanuele Valeriani, Nicola Potere, Matteo Candeloro, Silvia Spoto, Ettore Porreca, Anne WS Rutjes, Marcello Di Nisio
Section: Original article

Acute ischemic stroke is a major health burden worldwide due to high rates of ensuing hospitalizations, complications, disability, dependency, and death [1]. Venous thromboembolism (VTE), which comprises deep vein thrombosis (DVT) and pulmonary embolism (PE), represents a frequent complication in patients with stroke and is associated with significant morbidity and mortality [2]. In these patients, hospitalization, immobilization, and other medical sequelae deriving from the neurological deficits may increase VTE risk up to threefold compared to patients without stroke [3,4].

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