Published: 15 April 2021
Author(s): Agostino Di Ciaula, Federico Carbone, Harshitha Shanmugham, Emilio Molina-Molina, Leonilde Bonfrate, Stefano Ministrini, Fabrizio Montecucco, Piero Portincasa
Issue: May 2021
Section: Original article

Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease with a worldwide prevalence of about 30% [1]. NAFLD frequently occurs in overweight and obese individuals [2], and is often associated with dyslipidaemia, and insulin resistance [3,4]. Subjects with NAFLD have no signs of acute or chronic liver disease other than an excessive (>5%) accumulation of lipids – mainly triglycerides - in the liver and no other causes for secondary hepatic fat accumulation, including heavy alcohol consumption [5,6].

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