Published: 18 March 2021
Author(s): Diego Palumbo, Corrado Campochiaro, Alessandro Belletti, Alessandro Marinosci, Lorenzo Dagna, Alberto Zangrillo, Francesco De Cobelli, for the COVID-BioB Study Group
Issue: May 2021
Section: Letter to the Editor

Pneumothorax (PNX) and pneumomediastinum (PMD) have been frequently observed in mechanically ventilated patients with coronavirus disease 2019 (COVID-19)-related acute respiratory distress syndrome (ARDS), with a reported rate up to 24% [1]. No study has evaluated so far the exact rate of these events in non-intubated COVID-19 patients. We therefore decided to perform an observational study to investigate the rate of PNX/PMD in non-intubated COVID-19 patients and to compare the rate of PNX/PMN between patients admitted during the first and second Italian pandemic wave.

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