Published: 10 July 2021
Author(s): Luca Soraci, Francesco Corica, Andrea Corsonello, Francesca Remelli, Pasquale Abete, Giuseppe Bellelli, Mario Bo, Antonio Cherubini, Mauro Di Bari, Marcello Maggio, Anna Maria Martone, Maria Rosaria Rizzo, Giovanna Maria Manca, Andrea P Rossi, Antonella Zambon, Stefano Volpato, Francesco Landi, GLISTEN Group Investigators
Issue: October 2021
Section: Original Article

Older patients may often be affected by several chronic conditions, including chronic kidney disease (CKD), anemia, sarcopenia and neurological disorders [1–4], that are known to contribute to overall morbidity and mortality. Severity of kidney dysfunction in CKD was previously associated with poor prognosis in several geriatric populations [5, 6], but multiple co-occurring diseases may interact with kidney dysfunction to variably affect prognosis in older patients [7–9]. Current evidence suggests that some interactions between CKD, cognitive dysfunction, physical disability, anemia, and sarcopenia may differently affect outcomes [10–12].

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