Hereditary hemorrhagic telangiectasia (HHT) or Rendu–Osler–Weber syndrome (ORPHA:774) is a rare autosomal dominant vascular disease characterized by systemic telangiectases and larger vascular malformations (VMs) [1]. The hallmark of HHT is telangiectasis, which are dilated postcapillary venules directly connected with dilated arterioles losing the capillary bed [2]. HHT can be diagnosed either using the Curaçao clinical criteria (recurrent epistaxis, cutaneous/mucosal telangiectasia, visceral VMs, and a first-degree family member with HHT) or through molecular genetic test [2,3].
