Subclinical hypothyroidism, lipid metabolism and cardiovascular disease

Published: 28 December 2016
Author(s): Alessandro P Delitala, Giuseppe Fanciulli, Margherita Maioli, Giuseppe Delitala
Section: Narrative Review

Subclinical hypothyroidism is defined by elevated serum thyrotropin in presence of normal free thyroid hormones. Lipid metabolism is influenced by thyroid hormone and many reports showed that lipids status worsen along with TSH level. Subclinical hypothyroidism has been also linked to other cardiovascular risk factors such as alteration in blood pressure and increased atherosclerosis. Further evidences suggested that mild dysfunction of thyroid gland is associated with metabolic syndrome and heart failure.