European Journal of Internal Medicine

January 2018

26 Articles

No Section

COPD exacerbations in the emergency department: Epidemiology and related costs. A retrospective cohort multicentre study from the Italian Society of Emergency Medicine (SIMEU)

22 January 2018
Author(s): Federico Germini, Giacomo Veronese, Maura Marcucci, Daniele Coen, Deborah Ardemagni, Nicola Montano, Andrea Fabbri, SIMEU Study Group

Acute exacerbations of chronic obstructive pulmonary disease (AECOPDs) frequently cause patients with COPD to access the emergency department and have a negative impact on the course of the disease.... more

A red eye and a brown back: There's no smoke without a fire!

5 January 2018
Author(s): H.E. (Dorien) van Dongen, Daan J.L. van Twist

A 55-year-old woman with a history of psoriasis, hidradenitis suppurativa, and back pain was referred to our emergency department because of fever and pain around her left eye. She had no respiratory... more

Appropriateness of statin prescription in the elderly

5 January 2018
Author(s): M. Ruscica, C. Macchi, C. Pavanello, A. Corsini, A. Sahebkar, C.R. Sirtori

Statins, the most widely used drugs in the Western world, have become a pivotal component in the primary and secondary prevention of vascular diseases. Although benefits have been well documented in... more

Internal Medicine Flashcard

Mucocutaneous hyperpigmentation

8 January 2018
Author(s): Francisco Galeano-Valle, Lucía Higuera-Cabañes

A 43-year-old woman with a 1-year history of 6-kg weight loss and weakness was diagnosed with primary hypothyroidism and started levothyroxine one week before. She presented to the emergency... more

Nevus-like lesions on the lip and the foot

12 January 2018
Author(s): Nilufer Ozdemir Kutbay, Banu Sarer Yurekli, Ahmet Sever, Can Ceylan

Our 18-year-old male patient was admitted to our hospital with the complaints of impaired growth of body hair and erectile dysfunction. He was 1.77cm and 51kg with BMI of 16.7kg/m2. Micrognathia,... more

Podoconiosis: Nonfilarial endemic elephantiasis

19 January 2018
Author(s): Titilope Olanipekun, Haixia Qin, Mesfin Fransua

A 54-year-old male with medical history of hypertension was admitted for inability to walk and painless leg swelling. The swelling started in both feet and progressively extended to his mid legs.... more

Exfoliative esophagitis

4 January 2018
Author(s): Yusaku Kajihara

A 78-year-old woman presented to the author's hospital with epigastralgia. Vital signs were normal and the patient's abdomen was soft. The patient had taken dabigatran 110mg twice daily due to atrial... more

Two classical neurological syndromes following a stab wound

3 January 2018
Author(s): Matthew R. McCann, Mauricio F. Villamar

A previously healthy 28-year-old man presented to the trauma department after being stabbed in the head, neck, and torso by multiple assailants. He was able to speak and breathe independently.... more

The recurrent intertriginous rash

5 January 2018
Author(s): Kang Nien How, Anisha Bhullar

A 51years old lady presented to the dermatology department for recurrent painful, pruritic and malodourous erosive plaques in the intertriginous folds and scalp since the age of twelve years. Prior... more

Letter to the Editor

Chronic obstructive pulmonary disease and community acquired pneumonia: Additional studies are required

8 January 2018
Author(s): Javier de Miguel-Díez, Ana López-de-Andrés, Valentín Hernández-Barrera, Isabel Jiménez-Trujillo, Manuel Méndez-Bailón, José María de Miguel-Yanes, Rodrigo Jiménez-García

We have read the letter written by Santos et al. [1], in response to the manuscript previously published by us about the impact of COPD on outcomes in hospitalized patients with community-acquired... more

Pressure to publish in the biomedical scientific field: Ethical conflicts or a possible obsessive-compulsive disorder?

9 January 2018
Author(s): Salvatore Chirumbolo, Geir Bjørklund

Some author recently reported that pressure to publish in the scientific biomedical field may push down research quality and should debase any editorial policy that aims at discouraging competing... more

Microcytosis is important in screening of iron deficiency anemia

18 January 2018
Author(s): Lucia De Franceschi, Achille Iolascon, Ali Taher, Maria Domenica Cappellini

We have read with interest the observations by Jolobe O. on our recently review entitled “clinical management of iron deficiency anemia in adults: systemic review on advances in diagnosis and... more

Beyond cut-off values for hypertension… individualize interventions

15 January 2018
Author(s): Carlos Andrés Pineda-Cañar, Herney Andrés García-Perdomo

The recently proposed new classification and intervention for hypertension published by the ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Panel [1] have caused lots of controversy since it lowers... more

Association between unplanned readmission to a different hospital and all-cause mortality among older patients with ischemic heart disease: A nationwide claim study

19 January 2018
Author(s): Yeong Jun Ju, Hoo-Yeon Lee, Sang Ah Lee, Jaeyong Shin, Eun-Cheol Park

Up to one-third of patients are readmitted to a different hospital although it is unclear whether the readmission site affects subsequent outcomes. For example, although most patients are readmitted... more

Prognostic accuracy of qsofa according to the site of infection in older patient attended in Emergency Department

4 January 2018
Author(s): Angel Estella, Julio Gamazo-Del Rio, Jesús Álvarez-Manzanares, Agustín Julián-Jiménez, Juan González del Castillo

Early identification and intensive management of sepsis improve patient outcomes [1,2]. The quick sepsis-related organ failure assessment (qSOFA) score was developed to identify patients suspected of... more

Narrative Review

Medical use of cannabis and cannabinoids containing products – Regulations in Europe and North America

10 January 2018
Author(s): Ran Abuhasira, Liat Shbiro, Yuval Landschaft

In 1937, the United States of America criminalized the use of cannabis and as a result its use decreased rapidly. In recent decades, there is a growing interest in the wide range of medical uses of... more

Original Article

Female gender and mortality risk in decompensated heart failure

6 January 2018
Author(s): Domenico Scrutinio, Pietro Guida, Andrea Passantino, Rocco Lagioia, Rosa Raimondo, Mario Venezia, Enrico Ammirati, Fabrizio Oliva, Miriam Stucchi, Maria Frigerio

Still there is conflicting evidence about gender-related differences in prognosis among patients with heart failure. This prognostic uncertainty may have implications for risk stratification and... more

Effect of short- and long-term diabetes control on in-hospital and one year mortality rates in hospitalized patients with diabetic foot

10 January 2018
Author(s): Z. Feldbrin, M. Shargorodsky, J. Wainstein, D. Melnikov, G. Zandman-Goddard

It remains unclear whether diabetic patients with diabetic foot complications benefit from strict glycemic control during hospitalization The present study investigates the effect of short- and long-... more

Incidence of pheochromocytoma and sympathetic paraganglioma in the Netherlands: A nationwide study and systematic review

18 January 2018
Author(s): Annika M.A. Berends, Edward Buitenwerf, Ronald R. de Krijger, Nic J.G.M. Veeger, Anouk N.A. van der Horst-Schrivers, Thera P. Links, Michiel N. Kerstens

Recent years have seen major changes in clinical practice which may have affected the incidence rates of pheochromocytoma(PCC)/sympathetic paraganglioma(sPGL). There is, however, a lack of up-to-date... more

Effectiveness of guideline-consistent heart failure drug prescriptions at hospital discharge on 1-year mortality: Results from the EPICAL2 cohort study

2 January 2018
Author(s): Amandine Busson, Nathalie Thilly, Hervé Laborde-Castérot, François Alla, Ziyad Messikh, Isabelle Clerc-Urmes, Alexandre Mebazaa, Marc Soudant, Nelly Agrinier

We aimed to assess the effectiveness of recommended drug prescriptions at hospital discharge on 1-year mortality in patients with heart failure (HF) and reduced ejection fraction (HFREF).

Exercise transcutaneous oximetry significantly modifies the diagnostic hypotheses and impacts scheduled investigations or treatments of patients with exertional limb pain

4 January 2018
Author(s): Samir Henni, Guillaume Mahe, Christophe Lamotte, Remi Laurent, Alessandra Bura Riviere, Marion Aubourg, Gabrielle Sarlon, Damien Laneelle, Anne Long, Isabelle Signolet, Jean Picquet, Mathieu Feuilloy, Pierre Abraham

In lower extremity peripheral artery disease (PAD), transcutaneous oximetry at exercise (Ex-TcpO2) has been largely validated in research practice, but evidence of routine practice in various... more

Peripheral arterial disease is associated with higher mortality in patients with incident acute myocardial infarction

5 January 2018
Author(s): Lisa Dinser, Christa Meisinger, Ute Amann, Margit Heier, Christian Thilo, Bernhard Kuch, Annette Peters, Inge Kirchberger

Little data is available on short- and long-term survival in patients with peripheral arterial disease (PAD) after acute myocardial infarction (AMI). We aimed to examine the association of PAD and 28... more

Review Article

The therapeutic effects of Cannabis and cannabinoids: An update from the National Academies of Sciences, Engineering and Medicine report

9 January 2018
Author(s): Donald I. Abrams

The National Academies of Sciences, Engineering and Medicine conducted a rapid turn-around comprehensive review of recent medical literature on The Health Effects of Cannabis and Cannabinoids. The 16... more

The therapeutic potential of targeting the peripheral endocannabinoid/CB1 receptor system

11 January 2018
Author(s): Joseph Tam, Liad Hinden, Adi Drori, Shiran Udi, Shahar Azar, Saja Baraghithy

Endocannabinoids (eCBs) are internal lipid mediators recognized by the cannabinoid-1 and -2 receptors (CB1R and CB2R, respectively), which also mediate the different physiological effects of... more

Severe idiopathic pulmonary fibrosis: A clinical approach

18 January 2018
Author(s): R. Lipsi, D. Mazzola, A. Caminati, D. Elia, C. Lonati, S. Harari

Idiopathic pulmonary fibrosis (IPF) is a devastating progressive disease associated with a high mortality rate. Novel antifibrotic therapies have been recently demonstrated to slow disease... more

Practical considerations in medical cannabis administration and dosing

4 January 2018
Author(s): Caroline A. MacCallum, Ethan B. Russo

Cannabis has been employed medicinally throughout history, but its recent legal prohibition, biochemical complexity and variability, quality control issues, previous dearth of appropriately powered... more