Cytopenia induced by low-dose methotrexate: An analysis of 433 cases from the French pharmacovigilance database

Published: 23 July 2019
Author(s): Sophie Lalevée, Bénédicte Lebrun-Vignes, Corinne Simon, Delphine Laugier, Laurence Fardet, the French Network of Regional Centres of Pharmacovigilance
Issue: July 2019

Up to 5% of individuals exposed to low-dose methotrexate (MTX) (i.e., ≤30 mg/week) may develop cytopenia. However, MTX-induced cytopenia have been poorly described.