Published: 4 June 2016
Author(s): Grzegorz Helbig, Joanna Dziaczkowska-Suszek, Tomasz Francuz, Karolina Torba, Sławomira Kyrcz-Krzemień
Issue: June 2016
Section: Letter to the Editor

Hypereosinophilic syndrome (HES) is defined by 1) blood hypereosinophilia (HE), 2) HE-attributable organ damage/dysfunction and 3) the absence of other conditions or disorders which may be responsible for organ impairment. The lymphocytic variant of HES (L-HES) exhibits several features of reactive HES and is defined by the presence of an aberrant T-cells overproducing interleukin-5 (IL-5) or rarely other cytokines. Of note is, that the clonal T-cell receptor (TCR) by polymerase chain reaction (PCR) are frequently observed in these abnormal T-cells, but it is not a rule [1].

Relevant EFIM Publications

Clinical practice guidelines adaptation for internists - An EFIM methodology

Author(s): Wiktoria Leśniak, Laura Morbidoni, Dror Dicker, Ignacio Marín-León
Date:25 June 2020

The challenge of implementing Less is More medicine: A European perspective

Author(s): Omar Kherad, Nathan Peiffer-Smadja, Lina Karlafti, Margus Lember, Nathalie Van Aerde, Orvar Gunnarsson, Cristian Baicus, Miguel Bigotte Vieira, António Vaz-Carneiro, Antonio Brucato, Ivica Lazurova, Wiktoria Leśniak, Thomas Hanslik, Stephen Hewitt, Eleni Papanicolaou, Olga Boeva, Dror Dicker, Biljana Ivanovska, Pinar Yldiz, Patrick Lacor, Mark Cranston, Frauke Weidanz, Giorgio Costantino, Nicola Montano
Date:16 April 2020

Medical and surgical co-management – A strategy of improving the quality and outcomes of perioperative care

Author(s): Carmen Fierbinţeanu-Braticevicia, Matthias Raspeb, Alin Liviu Predac, Evija Livčāned, Leonid Lazebnike, Soňa Kiňováf, Evert- Jan de Kruijfg, Radovan Hojsh, Thomas Hansliki, Mine Durusu-Tanrioverj, Francesco Dentalik, Xavier Corbellal, Pietro Castellinom, Monica Bivoln, Stefano Bassettio, Vasco Barretop, Eduardo Montero Ruizq, Luis Camposr, The Working Group on Professional Issues and Quality of Care of the European Federation of Internal Medicine (EFIM)
Date:15 November 2018


More publications

What is EFIM?

The principal objectives of EFIM is to promote internal medicine on a scientific educational, ethical and professional level and to support internists in providing better care for patients throughout Europe.

Learn more

What is internal medicine?

The specialty of internal medicine covers a wide range of conditions affecting the internal organs of the body. Although some diseases specifically affect individual organs, the majority of common diseases. The internist must then be trained to recognise and manage a broad range of diseases and, with the aging population, many patients with chronic and multiple disorders.

Learn more

Internal Medicine meets Public

Under construction.

Coronavirus disease 2019 : short notice for public
Watch our webinars

Newsletters