Recipient liver function before liver transplantation influences post-transplantation survival in patients with HCC

Published: 30 May 2018
Author(s): Friedrich Foerster, Jens Mittler, Felix Darstein, Michael Heise, Jens U. Marquardt, Marcus-Alexander Wörns, Arndt Weinmann, Lina Sälter, Maria Hoppe-Lotichius, Stefan Heinrich, Roman Kloeckner, Michael B. Pitton, Jörn M. Schattenberg, Martin F. Sprinzl, Christoph Düber, Gerd Otto, Hauke Lang, Peter R. Galle, Tim Zimmermann
Issue: June 2018

Liver transplantation (LT) is a complex yet curative treatment for a subset of patients with hepatocellular carcinoma (HCC). Due to donor organ shortage, patients with HCC need to be carefully selected for LT. In European countries, selection of patients is based on the Milan criteria, and donor organs are allocated by Eurotransplant. In order to optimize the utilization of available liver grafts, the outcome of HCC patients after LT needs to be closely monitored and evaluated.