March 2020

28 Articles

No Section

Alcohol consumption and risk of incident atrial fibrillation: A population-based cohort study

6 March 2020
Author(s): Cecilia Johansson, Marcus M Lind, Marie Eriksson, Maria Wennberg, Jonas Andersson, Lars Johansson

AF is a common cardiac arrhythmia that has a prevalence of 3% and an incidence of 4 cases per 1000 person-years [1,2]. Over half of incident AF cases could potentially be avoided by optimizing or... more


The possible clinical impact of a threshold left atrial diameter associated with new AF in ESUS patients

17 March 2020
Author(s): Michela Giustozzi, Maurizio Paciaroni

Embolic stroke of undetermined source (ESUS) accounts for up of 25% of all ischaemic strokes and its risk of recurrence has been estimated to be approximately 5% per year [1,2]. The concept of ESUS... more

Point of care ultrasound training in internal medicine: Steps towards standardization

17 March 2020
Author(s): Charles M. LoPresti

Point of Care Ultrasound (POCUS) is rapidly gaining international acceptance in the field of internal medicine. Realizing POCUS's potential to decrease procedural complication rates [1–3] improve... more

Point-of-care ultrasound in internal medicine: Establishing standards for Europe

13 March 2020
Author(s): Irene W.Y. Ma, Gigi Liu

As internists grapple with the care needs of an increasingly complex patient population with multimorbidity [1], the need for a bedside tool that will allow a more comprehensive and better assessment... more

Beyond anticoagulant therapy. The not benign impact of atrial fibrillation on patients’ outcomes in a real world ‘scenario’

17 March 2020
Author(s): Stefano Fumagalli

Some weeks ago, while I was visiting an old lady with a first episode of atrial fibrillation (AF), a friend of mine, a very clever cardiologist and scientist, said: “Do not worry madam, you have an... more

Internal Medicine Flashcard

Young female patient with bilateral periorbital edema

5 March 2020
Author(s): Yasuhiro Kano, Takaie Kuki

A 19-year-old female patient presented to the emergency department with a one-week history of fever, malaise, and progressive eyelid swelling. She had no remarkable past medical history and seemed at... more

Skin rash and fever in a surgical patient

7 March 2020
Author(s): Joana Cordeiro e Cunha, Ana Lima Silva, João M. Mendes

A 45-year-old male recently diagnosed with colon cancer was admitted to the surgical ward with retroperitoneal abscess due to complicated retroperitoneal invasion. Percutaneous drainage of the... more

Letter to the Editor

Timing of repeat plasma sodium as a risk factor for eventual sodium overcorrection in patients with severe hyponatremia

17 March 2020
Author(s): Wenhui Huang, Robert Hawkins

The clinical risk factors for plasma sodium overcorrection in patients with severe hyponatremia are well described. Unfortunately, majority of these risk factors are non-modifiable at clinical... more

Post myocardial infarction infection: Can we predict it or not? Authors' reply

10 March 2020
Author(s): YiNing Dai, YuanHui Liu, Ning Tan, PengCheng He

We would like to appreciate Athanasios Manolis and Dimitrios Varvarousis for their interest in our work [1]. In our research, we included consecutive patients with ST-elevation myocardial infarction... more

Safety and efficacy of outpatient management for elderly patients with uncomplicated acute diverticulitis

18 March 2020
Author(s): Karolina Juszczyk, Kelsey Ireland, Bev Thomas, Hidde M. Kroon, Paul Hollington

Dear Editor:

Exploring the characteristics, global distribution and reasons for retraction of published articles involving human research participants: A literature survey

23 March 2020
Author(s): Bin Wang, Junkai Lai, Xiaoyan Yan, Feifei Jin, Chen Yao

Over the past few years, the issue of retractions has attracted the attention of researchers and many studies have reported the current state of retractions [1]. Many previous studies have analyzed... more

Iron deficiency in pregnancy and gastrointestinal cancer: addressing a common gap

23 March 2020
Author(s): O.A. Tiulienieva, C. Tsagkaris, A. Hoian

The article of Alexandre, Leo et al. [1] about the correlation of Iron Deficiency without Anemia (IDWA) with intestinal cancer was an interesting read. Essentially Iron Deficiency (ID) appears as a... more

The reliability of ultrasound compression test performed by general ICU nurses in the critically ill patients: A preliminary prospective clinical study

23 March 2020
Author(s): Roman Skulec, Alena Kohlova, Lenka Miksova, Vladimir Cerny

Deep venous thrombosis (DVT) is the common complication of intensive care in the critically ill patients. Despite thromboprophylactic measures, its incidence ranges from 5 to 32% [1]. One of the... more

Clinical course of primary immune thrombocytopenia with positive antiphospholipid antibodies: Author´s reply

23 March 2020
Author(s): Ana Clara Ladeira Cruz, Marina Pereira Colella, Erich Vinícius De Paula, Joyce Annichinno-Bizzachi, Fernanda Andrade Orsi

Dear Editor,

Turkish Society of Internal Medicine choosing wisely project

7 March 2020
Author(s): Pınar Yildiz, Mine Durusu Tanriover, Serhat Unal

Choosing Wisely® is a health initiative campaign that was established by the American Board of Internal Medicine (ABIM) Foundation that seeks to advance a national dialogue on avoiding unnecessary... more

The post-pulmonary embolism (Post-PE syndrome)

9 March 2020
Author(s): José Luis Alonso-Martínez, Francisco Javier Anniccherico-Sánchez, Miren Aránzazu Urbieta-Echezarreta

It is estimated that about 10 million of cases per year of venous thromboembolism (VTE) occur worldwide with substantial morbidity and mortality [1]. VTE affects mainly the older population with... more

Active smoking is not associated with severity of coronavirus disease 2019 (COVID-19)

17 March 2020
Author(s): Giuseppe Lippi, Brandon Michael Henry

In the ongoing coronavirus disease 2019 (COVID-19) pandemic, some unique clinical features have been described [1]. In a report of 44,672 cases from China, a case fatality rate of 2.8% for males... more

Rituximab-associated neuropathy: About two cases

17 March 2020
Author(s): Valentin Maisons, Saleh Kaysi

Rituximab is a type I anti-CD20 monoclonal antibody, which is primarily used for treating non-Hodgkin's B cell lymphoma [1]. Clinical efficacy, safety, and modulating effects on normal, malignant pre... more

Original Article

Impact of treatment strategies on long-term outcome of CTO patients

14 March 2020
Author(s): Christian Roth, Georg Goliasch, Stefan Aschauer, Clemens Gangl, Mohamed Ayoub, Klaus Distelmaier, Bernhard Frey, Irene M. Lang, Rudolf Berger, Kambis Mashayekhi, Miroslaw Ferenc, Christian Hengstenberg, Aurel Toma

Chronic total occlusions (CTO) are a common entity in patients with stable coronary artery disease undergoing coronary angiography with a point-prevalence between 15 and 30% [1–3]. CTO... more

Anticoagulation in thrombocytopenic patients with hematological malignancy: A multinational clinical vignette-based experiment

13 March 2020
Author(s): Avi Leader, Vincent ten Cate, Arina J ten Cate-Hoek, Erik A.M. Beckers, Galia Spectre, Cinzia Giaccherini, Anna Gurevich-Shapiro, Eilon Krashin, Pia Raanani, Harry C. Schouten, Anna Falanga, Hugo ten Cate

Thrombocytopenia in cancer patients with an indication for anticoagulation is not uncommon [1], and poses a unique clinical challenge. Clinical trials evaluating anticoagulants for treatment of... more

Clinical utility of fecal calprotectin in monitoring disease activity and predicting relapse in pregnant patients with inflammatory bowel diseases

20 March 2020
Author(s): Amihai Rottenstreich, Tali Mishael, Sorina Grisaru Granovsky, Benjamin Koslowsky, Hagai Schweistein, Guila Abitbol, Eran Goldin, Ariella Bar-Gil Shitrit

Inflammatory bowel disease (IBD) is frequently diagnosed among reproductive-aged women, with 25% of women conceiving after diagnosis [1]. Associations of IBD with pregnancy outcomes have been... more

Prevalence of the age-related diseases in older patients with acquired thrombotic thrombocytopenic purpura

19 March 2020
Author(s): Pasquale Agosti, Ilaria Mancini, Francesca Gianniello, Paolo Bucciarelli, Andrea Artoni, Barbara Ferrari, Silvia Pontiggia, Silvia Maria Trisolini, Luca Facchini, Cecilia Carbone, Flora Peyvandi, Italian Group of TTP Investigators

The prevalence of older patients with acquired thrombotic thrombocytopenic purpura (TTP) has increased as a consequence of significant improvements in disease diagnosis and drug availability. Patient... more

Acidosis predicts mortality independently from hyperlactatemia in patients with sepsis

3 March 2020
Author(s): Bernhard Wernly, Nadia Heramvand, Maryna Masyuk, Richard Rezar, Raphael Romano Bruno, Malte Kelm, David Niederseer, Michael Lichtenauer, Uta C Hoppe, Jan Bakker, Christian Jung

As septic patients show high mortality rates, timely risk prediction and stratification are crucial to initiating early, aggressive, and effective treatment in this high-risk patient collective [1].... more

Epidemiological trend of hepatitis C-related liver events in Spain (2000–2015): A nationwide population-based study

3 March 2020
Author(s): Irene Mate-Cano, Alejandro Alvaro-Meca, Pablo Ryan, Salvador Resino, Verónica Briz

Hepatitis C infection (HCV) is a global health issue that is probably underestimated because HCV infection is mostly asymptomatic. A recent report has estimated that globally there are around 71... more

Short-term mortality risk score for de novo acute heart failure (ESSIC-FEHF)

4 March 2020
Author(s): Susana García-Gutiérrez, Ane Antón-Ladislao, Raul Quiros, Antonio Lara, Irene Rilo, Miren Morillas, Nekane Murga, Maria Soledad Gallardo, Iratxe Lafuente, Urko Aguirre, Jose Maria Quintana, ESSIC –REDISSEC Group

Acute heart failure (AHF) is one of the most common reasons for emergency department (ED) attendance in Spain, 24% of patients being discharged home from the ED). AHF may present de novo, that is, as... more

Abnormal ankle-brachial index (ABI) predicts primary and secondary cardiovascular risk and cancer mortality

6 March 2020
Author(s): A. Visonà, A. De Paoli, U. Fedeli, D. Tonello, B. Zalunardo, N. Zanatta, R. Martini, R. Pesavento, S. Cuppini, M. Prior, S. Benazzi, C. Cimminiello, F. Avossa

An abnormal ankle-brachial pressure index (ABI) is a marker of the risk for increased total and cardiovascular (CV) mortality. However, it is not clear whether it is associated with an even worse... more

High prevalence of malnutrition in Internal Medicine wards – a multicentre ANUMEDI study

9 March 2020
Author(s): Ricardo Marinho, Ana Pessoa, Marta Lopes, João Rosinhas, João Pinho, Joana Silveira, Ana Amado, Sandra Silva, Bruno M.P.M. Oliveira, Aníbal Marinho, Harriët Jager-Wittenaar

Malnutrition has been described as a state resulting from lack of intake or uptake of nutrition that leads to altered body composition and body cell mass, leading to diminished physical and mental... more

Review Article

Statins and inflammatory bowel disease: Where do we stand?

6 March 2020
Author(s): Spyros Peppas, Daniele Piovani, Laurent Peyrin-Biroulet, Silvio Danese, Stefanos Bonovas

Inflammatory bowel disease (IBD) comprises immunologically mediated diseases characterized by a costly chronic course and frequent remissions and relapses [1]. Crohn's disease (CD) and ulcerative... more

Relevant EFIM Publications

The challenge of implementing Less is More medicine: A European perspective

Author(s): Omar Kherad, Nathan Peiffer-Smadja, Lina Karlafti, Margus Lember, Nathalie Van Aerde, Orvar Gunnarsson, Cristian Baicus, Miguel Bigotte Vieira, António Vaz-Carneiro, Antonio Brucato, Ivica Lazurova, Wiktoria Leśniak, Thomas Hanslik, Stephen Hewitt, Eleni Papanicolaou, Olga Boeva, Dror Dicker, Biljana Ivanovska, Pinar Yldiz, Patrick Lacor, Mark Cranston, Frauke Weidanz, Giorgio Costantino, Nicola Montano
Date:16 April 2020

Medical and surgical co-management – A strategy of improving the quality and outcomes of perioperative care

Author(s): Carmen Fierbinţeanu-Braticevicia, Matthias Raspeb, Alin Liviu Predac, Evija Livčāned, Leonid Lazebnike, Soňa Kiňováf, Evert- Jan de Kruijfg, Radovan Hojsh, Thomas Hansliki, Mine Durusu-Tanrioverj, Francesco Dentalik, Xavier Corbellal, Pietro Castellinom, Monica Bivoln, Stefano Bassettio, Vasco Barretop, Eduardo Montero Ruizq, Luis Camposr, The Working Group on Professional Issues and Quality of Care of the European Federation of Internal Medicine (EFIM)
Date:15 November 2018

Hospital ambulatory medicine: A leading strategy for Internal Medicine in Europe

Author(s): Xavier Corbellaa, Vasco Barretob, Stefano Bassettic, Monica Bivold, Pietro Castellinoe, Evert-Jan de Kruijff, Francesco Dentalig, Mine Durusu-Tanriöverh, Carmen Fierbinţeanu-Braticevicii, Thomas Hanslikj, Radovan Hojsk, Soňa Kiňovál, Leonid Lazebnikm, Evija Livčānen, Matthias Raspeo, Luis Camposp, The Working Group on Professional Issues and Quality of Care, European Federation of Internal Medicine (EFIM)
Date:14 April 2018

More publications

What is EFIM?

The principal objectives of EFIM is to promote internal medicine on a scientific educational, ethical and professional level and to support internists in providing better care for patients throughout Europe.

Learn more

What is internal medicine?

The specialty of internal medicine covers a wide range of conditions affecting the internal organs of the body. Although some diseases specifically affect individual organs, the majority of common diseases. The internist must then be trained to recognise and manage a broad range of diseases and, with the aging population, many patients with chronic and multiple disorders.

Learn more

Internal Medicine meets Public

Under construction.

Coronavirus disease 2019 : short notice for public
Watch our webinars