A 40-year-old man attended to the emergency department with a one-day history of generalized painful lesions. He was on tramadol for a clavicle fracture. Six hours before the appearance of the lesions, he self-administered etoricoxib due to poor pain control. Physical examination revealed multiple rounded violaceous patches and plaques with an erythematous rim distributed in the trunk and proximal aspects of the limbs. Many of them showed central epidermal detachment under tangential pressure (Fig. 1A).