IMN || Gastroenterology

Oral oligonucleotide shows efficacy, safety in Crohn’s

Posted on: 01/11/2014 - 15:36

VIENNA – Fourteen days of daily treatment with mongersen, an oral, antisense oligonucleotide, safely produced remissions in two-thirds of patients with Crohn’s disease in a phase II study with a...

Field of Interest: Gastroentero...

Type: News Item

Thiopurine for IBD linked to almost sixfold increase in lymphoma risk

Posted on: 01/11/2014 - 04:01

Patients with inflammatory bowel disease who took thiopurines for at least a year had an almost sixfold greater rate of lymphoma than did the general population, researchers reported in the November...

Field of Interest: Gastroentero...

Type: News Item

Thiopurine for IBD linked to almost sixfold increase in lymphoma risk

Posted on: 01/11/2014 - 04:01

Field of Interest: Oncology

Type: News Item

Higher dose of mesalamine can decrease risk of relapse for patients with quiescent ulcerative colitis

Posted on: 01/11/2014 - 04:01

Increasing dosages of mesalamine by 2.4 g/d for patients with quiescent ulcerative colitis can dramatically reduce concentrations of fecal calprotectin and ultimately decrease the likelihood of...

Field of Interest: Gastroentero...

Type: News Item

Hepatitis E virus mutation linked to ribavirin resistance

Posted on: 01/11/2014 - 04:01

A mutation in the hepatitis E virus might contribute to ribavirin treatment failure in transplant recipients with chronic HEV infection, according to a small study published in the November issue of...

Field of Interest: Gastroentero...

Type: News Item

Topical steroid might improve mucosal integrity in eosinophilic esophagitis

Posted on: 01/11/2014 - 04:01

Topical steroid therapy improved some indicators of mucosal integrity in patients with eosinophilic esophagitis, but proton pump inhibitor therapy did not, according to two studies reported in the...

Field of Interest: Gastroentero...

Type: News Item

Vedolizumab infection concerns diminish with growing data

Posted on: 27/10/2014 - 18:21

PHILADELPHIA – In long-term follow-up for the treatment of inflammatory bowel disease, the novel monoclonal antibody vedolizumab continues to remain free of serious infections or other signs of major...

Field of Interest: Gastroentero...

Type: News Item

Regurgitation controlled by transoral fundoplication

Posted on: 24/10/2014 - 13:39

PHILADELPHIA – The first trial conducted in gastroesophageal reflux diseases that employed control of regurgitation as a primary endpoint found a significant advantage for transoral fundoplication...

Field of Interest: Gastroentero...

Type: News Item

Drug-induced liver injury characterized from U.S. registry

Posted on: 24/10/2014 - 13:31

PHILADELPHIA – A registry created by the National Institutes of Health (NIH) to track idiosyncratic drug-induced liver injury (DILI) largely confirms the significant risks suggested by small studies...

Field of Interest: Gastroentero...

Type: News Item

Lynch syndrome screening underperformed in high-risk patients

Posted on: 22/10/2014 - 21:38

PHILADELPHIA– Despite evidence that screening reduces morbidity and mortality, even patients at high risk for Lynch syndrome (LS) are not being routinely evaluated, according to a comprehensive...

Field of Interest: Gastroentero...

Type: News Item

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