Additional predictive value of C-reactive protein to GRACE score in patients with acute coronary syndrome

Published: 6 August 2019
Author(s): Simone Persampieri, Diego Castini, Federica Valli, Ludovico Sabatelli, Stefano Carugo
Issue: August 2019
Section: Letter to the Editor

The awareness that active inflammation plays a major role in the initiation and progression of atherosclerosis dates back to the seminal observations of Ross et al. [1]. Although this concept relies on extensive experimental and clinical evidences, it's not, at yet, defined if the inflammatory process has a causative role in or simply accompanies the development of atherosclerotic plaques and myocardial injury. Among the numerous biomarkers evaluated, C-reactive protein (CRP) has been the most intensely studied.