Depression is often under-recognized in older patients, even if antidepressants (AD) are commonly prescribed, with a prevalence of use that increase with ageing . Nevertheless, even if a diagnosis of depression is established, inappropriate treatment can occur . Beers criteria are the most widely screening tools used to detect inappropriate prescription of drugs in people aged 65 years or more . Since 2010, attempts to adapt the Beers' criteria have been made in Europe [4,5]. Tricyclic drugs are the ADs to be always avoided in the elderly, owing to their anticholinergic side effects, such as cognitive impairment, delirium, urinary retention and falls .