Candidemia and invasive candidiasis in adults: A narrative review

Published: 6 July 2016
Author(s): Spinello Antinori, Laura Milazzo, Salvatore Sollima, Massimo Galli, Mario Corbellino
Issue: July 2016
Section: Review Article

Candidemia and invasive candidiasis are major causes of morbidity and mortality, and their incidence is increasing because of the growing complexity of patients. Five species of Candida (Candida albicans, Candida glabrata, Candida parapsilosis, Candida tropicalis and Candida krusei) account for more than 90% of all diagnosed cases, but their relative frequency varies depending on the population involved, geographical region, previous anti-fungal exposure, and patient age. The best evidence regarding the anti-fungal treatment for invasive candidiasis comes from randomized controlled trials in which more than 85% of the recruited patients had candidemia.