April 2018

23 Articles

No Section

Metabolic syndrome positively correlates with the risks of atherosclerosis and diabetes in a Chinese population

12 April 2018
Author(s): Sung-Sheng Tsai, Yu-Sheng Lin, Szu-Tah Chen, Pao-Hsien Chu

Published studies seldom tested the weight of different waist circumference (WC) cut-off values for the diagnosis of metabolic syndrome (MetS) in predicting clinical outcomes, including... more

Letter to Editor

Creating a list of low-value health care interventions according to medical students perspective

4 April 2018
Author(s): Romain Bonnet, Matthieu Laurencet, Jean-Michel Gaspoz, Omar Kherad

In 2010, The Choosing Wisely campaign, launched by the American Board of Internal Medicine sought to help physicians and patients engage in conversations about unnecessary tests, treatments and... more

Letter to the Editor

BIOACTIVE GLASS S53P4: a new opportunity for the treatment in the diabetic foot osteomyelitis

27 April 2018
Author(s): R. De Giglio, I. Stefani, T. Mondello, G. De Filippis, A. Mazzone

Diabetes mellitus is one of the major public health problems worldwide. With the aging of the population, improvements in living standards, and changes in lifestyle, the prevalence of the disease is... more

Erectile dysfunction: Imbalance between pro-angiogenic and anti-angiogenic factors in systemic sclerosis

24 April 2018
Author(s): Antonietta Gigante, Luca Navarini, Domenico Margiotta, Biagio Barbano, Antonella Afeltra, Edoardo Rosato

Systemic sclerosis (SSc) is an autoimmune disease characterized by fibrosis of skin and internal organs, endothelial and microvascular damage. Erectile dysfunction (ED) is a major issue for male with... more

Hypoalbuminemia is related to inflammation rather than malnutrition in sarcoidosis

24 April 2018
Author(s): Mehdi Mirsaeidi, Hesham R. Omar, Nadera Sweiss

Albumin is an acute phase reactant that is known to be influenced by many factors including the presence of an underlying inflammatory process. Inflammation was shown to reduce albumin levels... more

Relevance of the GOLD 2017 recommendations in habitual clinical practice

12 April 2018
Author(s): Juan Marco Figueira Gonçalves, Ignacio García Talavera

The new GOLD document (Global Initiative for Chronic Obstructive Lung Disease) 2017 [1] recommends guiding the treatment of chronic obstructive pulmonary disease (COPD) predominantly based on the... more

Use of oral anticoagulant drugs in older patients with atrial fibrillation in internal medicine wards

12 April 2018
Author(s): Marco Proietti, Stefania Antoniazzi, Valter Monzani, Paola Santalucia, Carlotta Franchi, SIM-AF Investigators

Atrial fibrillation (AF) is independently associated with a higher risk of morbidity and mortality, in particular with an increased risk of thromboembolic events [1]. Use of oral anticoagulant (OAC)... more

Cardiovascular implications of Zika virus infection

12 April 2018
Author(s): Dhrubajyoti Bandyopadhyay, Kumar Ashish, Sudeshna Ghosh, Adrija Hajra, Vivek Amit Modi

Zika virus(ZIKV) came into the picture in the human race for last many decades, but the World Health Organization announced it as a matter of public health emergency of global concern in February... more

High body mass index, healthy metabolic profile and low visceral adipose tissue: The paradox is to call it obesity again

7 April 2018
Author(s): Massimo Leggio, Mario Lombardi, Elisa Caldarone, Andrea Mazza, Augusto Fusco

During the last three decades, the worldwide prevalence of obesity has nearly doubled, and the mean body mass index has increased worldwide by 0.4 kg/m2 per decade for men and 0.5 kg/m2 per decade... more

Agreement between diseases-centered and multidimensional models of care in disadvantaged settings

4 April 2018
Author(s): Marco Canevelli, Francesca Remiddi, Sebastjan Mjekaj, Nicola Vanacore, Giuseppe Bruno, Matteo Cesari

The concept of disease has traditionally been representing the main focus of medicine and center of care. In fact, the clinical decision process largely relies on the diagnosis, treatment, and... more

An increase in diagnostic JAK2 V617F mutation testing: Is masked polycythaemia vera the explanantion?

2 April 2018
Author(s): Stephen E. Langabeer

It is now nearly two years since the publication of the 2016 revision to the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia [1] with one of the most... more

Renal dysfunction predicts mortality in type 2 diabetic patients suffering from an acute ischemic stroke

2 April 2018
Author(s): Tanja Hojs Fabjan, Meta Penko, Radovan Hojs

The prevalence of diabetes is increasing and has already reached pandemic proportions. Chronic kidney disease is also an important public health problem, with an estimated global prevalence of... more

Narrative Review

Cholecystectomy and risk of metabolic syndrome

26 April 2018
Author(s): Agostino Di Ciaula, Gabriella Garruti, David Q.-H. Wang, Piero Portincasa

The gallbladder physiologically concentrates and stores bile during fasting and provides rhythmic bile secretion both during fasting and in the postprandial phase to solubilize dietary lipids and fat... more

Human serum albumin in cardiovascular diseases

19 April 2018
Author(s): Stephane Arques

Cardiovascular diseases are the leading cause of death worldwide. Endothelial dysfunction, inflammation and oxidative stress are at the forefront in the onset and development of atherosclerosis and... more

Iron deficiency in chronic and acute heart failure: A contemporary review on intertwined conditions

19 April 2018
Author(s): Gonçalo J.L. Cunha, Bruno M.L. Rocha, Luiz Menezes Falcão

Iron Deficiency (ID) is increasingly recognized as a prevalent comorbid condition in Heart Failure (HF). Despite this, the pathophysiological mechanisms for progressive ID in either chronic or acute... more

Is there a role for intervention radiology for the treatment of lower limb deep vein thrombosis in the era of direct oral anticoagulants? A comprehensive review

11 April 2018
Author(s): Marco Marietta, Elisa Romagnoli, Benilde Cosmi, Valeria Coluccio, Mario Luppi

Despite recent advances in the treatment of Deep Vein Thrombosis (DVT) provided by Direct Oral Anticoagulants (DOAC), a substantial proportion of lower limb DVT patients will develop some degree of... more

Original Article

Hospital ambulatory medicine: A leading strategy for Internal Medicine in Europe

14 April 2018
Author(s): Xavier Corbella, Vasco Barreto, Stefano Bassetti, Monica Bivol, Pietro Castellino, Evert-Jan de Kruijf, Francesco Dentali, Mine Durusu-Tanriöver, Carmen Fierbinţeanu-Braticevici, Thomas Hanslik, Radovan Hojs, Soňa Kiňová, Leonid Lazebnik, Evija Livčāne, Matthias Raspe, Luis Campos, The Working Group on Professional Issues and Quality of Care, European Federation of Internal Medicine (EFIM)

Addressing the current collision course between growing healthcare demands, rising costs and limited resources is an extremely complex challenge for most healthcare systems worldwide. Given the... more

Hyponatraemia is independently associated with in-hospital mortality in patients with pneumonia

13 April 2018
Author(s): Martin Müller, Joerg C. Schefold, Viviane Guignard, Aristomenis K. Exadaktylos, Carmen A. Pfortmueller

Hyponatraemia on hospital admission has been shown to be a risk factor for illness severity in critically ill patients. The aim of the present study was to investigate whether hyponatraemia on... more

Temporal trends of time in therapeutic range and incidence of cardiovascular events in patients with non-valvular atrial fibrillation

11 April 2018
Author(s): Daniele Pastori, Alessio Farcomeni, Mirella Saliola, Francesco Del Sole, Pasquale Pignatelli, Francesco Violi, Gregory Y.H. Lip, ATHERO-AF Study Group

Optimal time in therapeutic range (TTR) of vitamin K antagonists (VKAs) is crucial for cardiovascular events (CVEs) prevention in non-valvular atrial fibrillation (NVAF). The relationship between... more

Impact of syncope and pre-syncope on short-term mortality in patients with acute pulmonary embolism

11 April 2018
Author(s): Loris Roncon, Marco Zuin, Franco Casazza, Cecilia Becattini, Claudio Bilato, Pietro Zonzin

Syncope and pre-syncope are well-known symptoms of acute pulmonary embolism (PE). However, data about their impact on short-term mortality are scant. We assess the short-term mortality (30-day) for... more

Clinical outcomes of Clostridium difficile infection according to strain type. A prospective study in medical wards

9 April 2018
Author(s): S. Serafino, D. Consonni, M. Migone De Amicis, F. Sisto, G. Domeniconi, S. Formica, M. Zarantonello, A. Maraschini, M.D. Cappellini, P. Spigaglia, F. Barbanti, S. Castaldi, G. Fabio

To describe clinical characteristics and outcome of Clostridium difficile infection (CDI) patients in Internal Medicine, to identify ribotypes (RTs); to evaluate the association between RT and... more

Prognostic relevance of glomerular filtration rate estimation obtained through different equations in hospitalized elderly patients

9 April 2018
Author(s): Paolo Gallo, Antonio De Vincentis, Claudio Pedone, Alessandro Nobili, Mauro Tettamanti, Umberto Vespasiani Gentilucci, Antonio Picardi, Pier Mannuccio Mannucci, Raffaele Antonelli Incalzi, REPOSI Investigators

The estimated glomerular filtration rate (eGFR) is a predictor of important outcomes and its reduction has been associated with the risk of all-cause mortality in both general population and elderly... more

The link between COPD and ankylosing spondylitis: A population based study

6 April 2018
Author(s): Kassem Sharif, Abdulla Watad, Shmuel Tiosano, Yarden Yavne, Anna Blokh Kerpel, Doron Comaneshter, Arnon D. Cohen, Howard Amital

Ankylosing spondylitis (AS) is one of the most common and severe subtypes of the spondyloarthropathies. Extra-articular involvement among AS patients, including lung disease, has been described... more


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