April 2018
23 ArticlesNo Section
Metabolic syndrome positively correlates with the risks of atherosclerosis and diabetes in a Chinese population
Published studies seldom tested the weight of different waist circumference (WC) cut-off values for the diagnosis of metabolic syndrome (MetS) in predicting clinical outcomes, including... more
Letter to Editor
Creating a list of low-value health care interventions according to medical students perspective
In 2010, The Choosing Wisely campaign, launched by the American Board of Internal Medicine sought to help physicians and patients engage in conversations about unnecessary tests, treatments and... more
Letter to the Editor
BIOACTIVE GLASS S53P4: a new opportunity for the treatment in the diabetic foot osteomyelitis
Diabetes mellitus is one of the major public health problems worldwide. With the aging of the population, improvements in living standards, and changes in lifestyle, the prevalence of the disease is... more
Erectile dysfunction: Imbalance between pro-angiogenic and anti-angiogenic factors in systemic sclerosis
Systemic sclerosis (SSc) is an autoimmune disease characterized by fibrosis of skin and internal organs, endothelial and microvascular damage. Erectile dysfunction (ED) is a major issue for male with... more
Hypoalbuminemia is related to inflammation rather than malnutrition in sarcoidosis
Albumin is an acute phase reactant that is known to be influenced by many factors including the presence of an underlying inflammatory process. Inflammation was shown to reduce albumin levels... more
Relevance of the GOLD 2017 recommendations in habitual clinical practice
The new GOLD document (Global Initiative for Chronic Obstructive Lung Disease) 2017 [1] recommends guiding the treatment of chronic obstructive pulmonary disease (COPD) predominantly based on the... more
Use of oral anticoagulant drugs in older patients with atrial fibrillation in internal medicine wards
Atrial fibrillation (AF) is independently associated with a higher risk of morbidity and mortality, in particular with an increased risk of thromboembolic events [1]. Use of oral anticoagulant (OAC)... more
Cardiovascular implications of Zika virus infection
Zika virus(ZIKV) came into the picture in the human race for last many decades, but the World Health Organization announced it as a matter of public health emergency of global concern in February... more
High body mass index, healthy metabolic profile and low visceral adipose tissue: The paradox is to call it obesity again
During the last three decades, the worldwide prevalence of obesity has nearly doubled, and the mean body mass index has increased worldwide by 0.4 kg/m2 per decade for men and 0.5 kg/m2 per decade... more
Agreement between diseases-centered and multidimensional models of care in disadvantaged settings
The concept of disease has traditionally been representing the main focus of medicine and center of care. In fact, the clinical decision process largely relies on the diagnosis, treatment, and... more
Renal dysfunction predicts mortality in type 2 diabetic patients suffering from an acute ischemic stroke
The prevalence of diabetes is increasing and has already reached pandemic proportions. Chronic kidney disease is also an important public health problem, with an estimated global prevalence of... more
An increase in diagnostic JAK2 V617F mutation testing: Is masked polycythaemia vera the explanantion?
It is now nearly two years since the publication of the 2016 revision to the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia [1] with one of the most... more
Narrative Review
Cholecystectomy and risk of metabolic syndrome
The gallbladder physiologically concentrates and stores bile during fasting and provides rhythmic bile secretion both during fasting and in the postprandial phase to solubilize dietary lipids and fat... more
Human serum albumin in cardiovascular diseases
Cardiovascular diseases are the leading cause of death worldwide. Endothelial dysfunction, inflammation and oxidative stress are at the forefront in the onset and development of atherosclerosis and... more
Iron deficiency in chronic and acute heart failure: A contemporary review on intertwined conditions
Iron Deficiency (ID) is increasingly recognized as a prevalent comorbid condition in Heart Failure (HF). Despite this, the pathophysiological mechanisms for progressive ID in either chronic or acute... more
Is there a role for intervention radiology for the treatment of lower limb deep vein thrombosis in the era of direct oral anticoagulants? A comprehensive review
Despite recent advances in the treatment of Deep Vein Thrombosis (DVT) provided by Direct Oral Anticoagulants (DOAC), a substantial proportion of lower limb DVT patients will develop some degree of... more
Original Article
Hospital ambulatory medicine: A leading strategy for Internal Medicine in Europe
Addressing the current collision course between growing healthcare demands, rising costs and limited resources is an extremely complex challenge for most healthcare systems worldwide. Given the... more
Hyponatraemia is independently associated with in-hospital mortality in patients with pneumonia
Hyponatraemia on hospital admission has been shown to be a risk factor for illness severity in critically ill patients. The aim of the present study was to investigate whether hyponatraemia on... more
Temporal trends of time in therapeutic range and incidence of cardiovascular events in patients with non-valvular atrial fibrillation
Optimal time in therapeutic range (TTR) of vitamin K antagonists (VKAs) is crucial for cardiovascular events (CVEs) prevention in non-valvular atrial fibrillation (NVAF). The relationship between... more
Impact of syncope and pre-syncope on short-term mortality in patients with acute pulmonary embolism
Syncope and pre-syncope are well-known symptoms of acute pulmonary embolism (PE). However, data about their impact on short-term mortality are scant. We assess the short-term mortality (30-day) for... more
Prognostic relevance of glomerular filtration rate estimation obtained through different equations in hospitalized elderly patients
The estimated glomerular filtration rate (eGFR) is a predictor of important outcomes and its reduction has been associated with the risk of all-cause mortality in both general population and elderly... more
Clinical outcomes of Clostridium difficile infection according to strain type. A prospective study in medical wards
To describe clinical characteristics and outcome of Clostridium difficile infection (CDI) patients in Internal Medicine, to identify ribotypes (RTs); to evaluate the association between RT and... more
The link between COPD and ankylosing spondylitis: A population based study
Ankylosing spondylitis (AS) is one of the most common and severe subtypes of the spondyloarthropathies. Extra-articular involvement among AS patients, including lung disease, has been described... more