An 81-year-old man presented to the author's hospital with one-week history of fever, non-productive cough and intermittent desaturations. This patient has known penicillin allergy, chronic hepatitis B and previous cholecystectomy. Five weeks before, the patient was admitted for polymicrobial bacteremia (Escherichia coli, Morganella morganii and Enterococccus casseliflavus) secondary to a multiloculated liver abscess that was not amenable to drainage. Since then, he had been on daptomycin for five weeks and ertapenem for ten days.