Published: 26 April 2019
Author(s): Hasan Eruzun, İlkim Deniz Toprak, Yücel Arman, Uğur Yılmaz, Mustafa Özcan, Yasin Kutlu, Sedat Irmak, Orkide Kutlu, Şengül Aydın Yoldemir, Özgür Altun, Eylem Özgün Çil, Tufan Tükek
Issue: April 2019
Section: Original Article

Endotrophin, a type VI collagen cleavage product, has fibrosis, and insulin resistance effects. Type VI collagen also plays a role in cardiac fibrosis. In this study, we aimed to investigate the role of endotrophin in the pathogenesis of cardiac fibrosis by determining its levels in patients with heart failure with reduced and mid-range ejection fraction (EF). We also aimed to determine the possible association between endotrophin and treatment that prevents ventricular fibrosis.

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