Published: 3 August 2017
Author(s): Audrey Benyamine, Daniel Bertin, Xavier Heim, Brigitte Granel, Nathalie Bardin
Issue: August 2017
Section: Letter to the Editor

Systemic sclerosis (SSc) is a chronic autoimmune disease characterised by skin and internal organs fibrosis, vascular damage and positive antinuclear autoantibodies (ANAs). The classical antigenic specificities of ANAs are anti-centromere (ACA), anti-topoisomerase I antibodies (anti-topo I) and the more recently described anti-RNA polymerase III antibodies (anti-RNAPIII).

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