A brain mass had been diagnosed to a 62years old man after an epileptic fit and subsequent comatose status. The mass had been excised; it was an anaplastic astrocytoma. After chemotherapy and radiotherapy cycles, he arrived at the emergency department of our hospital suffering from fever and ingravescent dyspnea. On admission his body temperature was 37.5°C, blood pressure and heart rate were normal and respiratory rate was 35 breaths per minute. Laboratory exam underlined pancytopenia and elevated C-reactive protein (CRP 19.7mg/L; norm: <0.3).