February 2017

23 Articles

No Section

Heritability of the femoral intima media thickness

22 February 2017
Author(s): Bence Fejer, Adam D Tarnoki, David L Tarnoki, Pierleone Lucatelli, Levente Littvay, Pal Maurovich-Horvat, Adam L Jermendy, Attila Kovacs, Erika Godor, Corrado Fagnani, Maria A Stazi, Andrea A Molnar, Fabrizio Fanelli, Carlo Cirelli, Filippo Farina, Claudio Baracchini, Giorgio Meneghetti, Giacomo Pucci, Gyorgy Jermendy, Bela Merkely, Giuseppe Schillaci, Emanuela Medda

The measurement of femoral intima-media thickness (IMT) is underutilized in the clinical practice, although it is a surrogate marker of cardiovascular disease.

Mastro Adamo, the Counterfeiter of Coins, had cirrhosis as described in Dante's Inferno (13th century Florence)

10 February 2017
Author(s): R. Bianucci, A. Perciaccante, P. Charlier, O. Appenzeller, D. Lippi

Ascites, the accumulation of serous fluid in the peritoneal cavity, occurs in many clinical settings such as congestive heart failure, chronic liver disease, nephrotic syndrome, malnutrition with... more

Internal Flash Card

The target sign in bowel obstruction

24 February 2017
Author(s): Zishan Sheikh, Mehtab Ahmad

A 64year old man presented with vomiting and colicky right upper abdominal pain radiating to his back. He had had these symptoms intermittently for three months, but they had acutely worsened over... more

Internal Medicine Flashcard

A forgotten old disease

24 February 2017
Author(s): Juan Carlos Cataño, Sara Isabel Gomez

An 81-year-old diabetic woman, presented to the out-patient clinic with a 10-year history of glove-like anesthesia in both hands. This neurologic deficit was reported to be accompanied by the... more

An elderly woman with ulceronodular rash

24 February 2017
Author(s): Antonio Faraone, Alberto Fortini

An 86-year-old woman affected by mild cognitive impairment presented to our institution with complaints of intense headache, vomiting and fever since 2days, complicating a 4-month history of mucosal... more

An elephantine problem

24 February 2017
Author(s): Manish Kumar Gaur, Aakanksha Goel, Sanjay Gupta

A 40-year old male belonging to northern India presented to the Emergency Department with multiple wounds on the feet. He had history of long standing swelling of both lower limbs. He had no recent... more

Paget's bone disease is not always the culprit

6 February 2017
Author(s): Agostino Gaudio, Luca Zanoli, Carmelo Erio Fiore

A 48-year-old woman, who was previously diagnosed with Paget's bone disease, referred to our Metabolic Bone Diseases Outpatient Clinic complaining of chronic, non-traumatic pain at the left foot.... more

Internal Medicine Flashcards

Unilateral abdominal bulge with sharp pain

24 February 2017
Author(s): Masaki Tago, Hidetoshi Aihara, Shun Yamashita

A 64-year-old man presented with sharp pain and progressive bulging in his right lower quadrant of the abdomen for three days (Fig. 1). He was smoker and he underwent appendicectomy about 50years ago... more

Letter to the Editor

Gender beliefs in medical students

26 February 2017
Author(s): Benedikt W. Pelzer, Kristina Mickevičiūtė

2015 the Lancet Commission Women and Health stated the important role of women in health care [1]. Following that the UN launched it's ‘Global Strategy for Women's, Children's and Adolescent's health... more

Applicability of the results of thrombophilia studies in clinical practice

24 February 2017
Author(s): Marc Sorigue, Edurne Sarrate, Cristian Morales-Indiano, Lidia Ruiz-Garcia, Elisa Orna

The factor V G1691A (factor V Leiden, FVL) and factor II G20210A gain-of-function mutations are the most frequent forms of inherited thrombophilia [1,2]. However, considering their prevalence in the... more

Gastrointestinal bleeding during DOACs-anticoagulant therapy. Is there nothing so bad that is not good for something?

24 February 2017
Author(s): Federico Pasin, Sophie Testa, Pietro Capone, Elena Iiritano, Roberto Grassia

Gastrointestinal (GI) bleeding is a common adverse event associated with conventional anticoagulants, such as vitamin K antagonist (VKA) (e.g. warfarin) [1]. Most such bleeding events are reported to... more

Attention and postural balance are much more affected in older than in younger adults with mild or moderate chronic hyponatremia

16 February 2017
Author(s): B. Renneboog, L. Sattar, G. Decaux

Mild chronic hyponatremia is associated with fall [1] and bone fracture [2]. This seems to be related to gait alteration, attention deficit and osteoporosis [1–3].

Activation and quantification of human brown adipose tissue: Methodological considerations for between studies comparisons

16 February 2017
Author(s): Borja Martinez-Tellez, Guillermo Sanchez-Delgado, Mariëtte R. Boon, Patrick C.N. Rensen, Jonatan R. Ruiz

We read with interest the study by Bahler et al. [1] that discusses the findings observed in two studies comparing brown adipose tissue (BAT) activity and volume in healthy young white Caucasians and... more

AA amyloidosis is an emerging cause of nephropathy in obese patients

14 February 2017
Author(s): Katia Stankovic Stojanovic, Sophie Georgin-Lavialle, Christine Poitou, David Buob, Serge Amselem, Gilles Grateau, The AMYLOB Study Group

Dear Sir,

Pioglitazone: Good news for diabetic patients with stroke?

13 February 2017
Author(s): Luis Castilla-Guerra, María del Carmen Fernandez-Moreno, Miguel Angel Colmero-Camacho

Disorders of glucose metabolism are highly prevalent among patients with established cerebrovascular disease. Up to 60% to 70% of patients may have dysglycemic state [1]. However, to date,... more

Risk factors for unintentional medication discrepancies at hospital admission: A matched case-control study

10 February 2017
Author(s): Carina Carvalho Silvestre, Lincoln Marques Cavalcante Santos, Rafaella de Oliveira Santos Silva, Genival Araújo dos Santos Jr, Sabrina Joany Felizardo Neves, Alfredo Dias de Oliveira-Filho, Iza Maria Fraga Lobo, Divaldo Pereira de Lyra Jr

Unintentional medication discrepancies (UMD) are defined as erroneous and unjustified medication changes between the medication use history and the admission medication orders. UMD (e.g., medication... more

Influence of anti-TNF therapy on bone metabolism in patients with inflammatory bowel disease

4 February 2017
Author(s): Beatriz Castro, Montserrat Rivero, Javier Crespo, J. Antonio Riancho, Carmen Valero

Several studies conclude that patients with inflammatory bowel disease (IBD) are at an increased risk of osteoporosis (30–50%) [1] and fractures (1.3 to 2.5 times) [2]. Different factors can be... more

Narrative Review

Use, misuse and abuse of diuretics

21 February 2017
Author(s): Ettore Bartoli, Luca Rossi, Daniele Sola, Luigi Castello, Pier Paolo Sainaghi, Carlo Smirne

Resolution of edema requires a correct interpretation of body fluids-related renal function, to excrete the excess volume while restoring systemic hemodynamics and avoiding renal failure. In heart... more

Physical activity and cardiovascular prevention: Is healthy urban living a possible reality or utopia?

16 February 2017
Author(s): Silvio Buscemi, Carla Giordano

Favoring correct lifestyles is the most important measure to contrast cardiovascular diseases and the epidemic of high cardiovascular risk conditions, such as obesity, diabetes, and hypertension.... more

Original Article

Guideline-adherent therapy for stroke prevention in atrial fibrillation in different health care settings: Results from RAMSES study

24 February 2017
Author(s): Özcan Başaran, Volkan Dogan, Murat Biteker, Fatma Özpamuk Karadeniz, Ahmet İlker Tekkesin, Yasin Çakıllı, Ceyhan Türkkan, Mehmet Hamidi, Vahit Demir, Mustafa Ozan Gürsoy, Müjgan Tek Öztürk, Gökhan Aksan, Sabri Seyis, Mehmet Ballı, Mehmet Hayri Alıcı, Serdar Bozyel, Cevat Kırma, Collaborators

No studies have been conducted in Turkey to compare the quality of stroke prevention therapies provided in different healthcare settings in patients with atrial fibrillation (AF). Therefore, we aimed... more

Colorectal neoplasm in cases of Clostridium septicum and Streptococcus gallolyticus subsp. gallolyticus bacteraemia

21 February 2017
Author(s): Juan Corredoira, Imma Grau, José F. Garcia-Rodriguez, María Jose García-País, Ramón Rabuñal, Carmen Ardanuy, Fernando García-Garrote, Amparo Coira, Maria Pilar Alonso, Annemarie Boleij, Roman Pallares

Bacteremia with Clostridium septicum (CS) and Streptococcus gallolyticus subsp. gallolyticus (SGG) have both been associated with colorectal neoplasms (CRN) and colonoscopic examination is advised,... more

A modified Elixhauser score for predicting in-hospital mortality in internal medicine admissions

8 February 2017
Author(s): Fabio Fabbian, Alfredo De Giorgi, Elisa Maietti, Massimo Gallerani, Marco Pala, Rosaria Cappadona, Roberto Manfredini, Ugo Fedeli

In-hospital mortality (IHM) is an indicator of the quality of care provided. The two most widely used scores for predicting IHM by International Classification of Diseases (ICD) codes are the... more

Comparison of late mortality after transcatheter aortic valve implantation versus surgical aortic valve replacement: Insights from a meta-analysis

4 February 2017
Author(s): Tomo Ando, Hisato Takagi, Representing ALICE (All-Literature Investigation of Cardiovascular Evidence) Group

Transcatheter aortic valve implantation (TAVI) has shown non-inferior late mortality in severe aortic stenosis (AS) patients in intermediate to inoperable risk for surgery compared to surgical aortic... more


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