February 2017
23 ArticlesNo Section
Heritability of the femoral intima media thickness
The measurement of femoral intima-media thickness (IMT) is underutilized in the clinical practice, although it is a surrogate marker of cardiovascular disease.
Mastro Adamo, the Counterfeiter of Coins, had cirrhosis as described in Dante's Inferno (13th century Florence)
Ascites, the accumulation of serous fluid in the peritoneal cavity, occurs in many clinical settings such as congestive heart failure, chronic liver disease, nephrotic syndrome, malnutrition with... more
Internal Flash Card
The target sign in bowel obstruction
A 64year old man presented with vomiting and colicky right upper abdominal pain radiating to his back. He had had these symptoms intermittently for three months, but they had acutely worsened over... more
Internal Medicine Flashcard
A forgotten old disease
An 81-year-old diabetic woman, presented to the out-patient clinic with a 10-year history of glove-like anesthesia in both hands. This neurologic deficit was reported to be accompanied by the... more
An elderly woman with ulceronodular rash
An 86-year-old woman affected by mild cognitive impairment presented to our institution with complaints of intense headache, vomiting and fever since 2days, complicating a 4-month history of mucosal... more
An elephantine problem
A 40-year old male belonging to northern India presented to the Emergency Department with multiple wounds on the feet. He had history of long standing swelling of both lower limbs. He had no recent... more
Paget's bone disease is not always the culprit
A 48-year-old woman, who was previously diagnosed with Paget's bone disease, referred to our Metabolic Bone Diseases Outpatient Clinic complaining of chronic, non-traumatic pain at the left foot.... more
Internal Medicine Flashcards
Unilateral abdominal bulge with sharp pain
A 64-year-old man presented with sharp pain and progressive bulging in his right lower quadrant of the abdomen for three days (Fig. 1). He was smoker and he underwent appendicectomy about 50years ago... more
Letter to the Editor
Gender beliefs in medical students
2015 the Lancet Commission Women and Health stated the important role of women in health care [1]. Following that the UN launched it's ‘Global Strategy for Women's, Children's and Adolescent's health... more
Applicability of the results of thrombophilia studies in clinical practice
The factor V G1691A (factor V Leiden, FVL) and factor II G20210A gain-of-function mutations are the most frequent forms of inherited thrombophilia [1,2]. However, considering their prevalence in the... more
Gastrointestinal bleeding during DOACs-anticoagulant therapy. Is there nothing so bad that is not good for something?
Gastrointestinal (GI) bleeding is a common adverse event associated with conventional anticoagulants, such as vitamin K antagonist (VKA) (e.g. warfarin) [1]. Most such bleeding events are reported to... more
Attention and postural balance are much more affected in older than in younger adults with mild or moderate chronic hyponatremia
Mild chronic hyponatremia is associated with fall [1] and bone fracture [2]. This seems to be related to gait alteration, attention deficit and osteoporosis [1–3].
Activation and quantification of human brown adipose tissue: Methodological considerations for between studies comparisons
We read with interest the study by Bahler et al. [1] that discusses the findings observed in two studies comparing brown adipose tissue (BAT) activity and volume in healthy young white Caucasians and... more
AA amyloidosis is an emerging cause of nephropathy in obese patients
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Pioglitazone: Good news for diabetic patients with stroke?
Disorders of glucose metabolism are highly prevalent among patients with established cerebrovascular disease. Up to 60% to 70% of patients may have dysglycemic state [1]. However, to date,... more
Risk factors for unintentional medication discrepancies at hospital admission: A matched case-control study
Unintentional medication discrepancies (UMD) are defined as erroneous and unjustified medication changes between the medication use history and the admission medication orders. UMD (e.g., medication... more
Influence of anti-TNF therapy on bone metabolism in patients with inflammatory bowel disease
Several studies conclude that patients with inflammatory bowel disease (IBD) are at an increased risk of osteoporosis (30–50%) [1] and fractures (1.3 to 2.5 times) [2]. Different factors can be... more
Narrative Review
Use, misuse and abuse of diuretics
Resolution of edema requires a correct interpretation of body fluids-related renal function, to excrete the excess volume while restoring systemic hemodynamics and avoiding renal failure. In heart... more
Physical activity and cardiovascular prevention: Is healthy urban living a possible reality or utopia?
Favoring correct lifestyles is the most important measure to contrast cardiovascular diseases and the epidemic of high cardiovascular risk conditions, such as obesity, diabetes, and hypertension.... more
Original Article
Guideline-adherent therapy for stroke prevention in atrial fibrillation in different health care settings: Results from RAMSES study
No studies have been conducted in Turkey to compare the quality of stroke prevention therapies provided in different healthcare settings in patients with atrial fibrillation (AF). Therefore, we aimed... more
Colorectal neoplasm in cases of Clostridium septicum and Streptococcus gallolyticus subsp. gallolyticus bacteraemia
Bacteremia with Clostridium septicum (CS) and Streptococcus gallolyticus subsp. gallolyticus (SGG) have both been associated with colorectal neoplasms (CRN) and colonoscopic examination is advised,... more
A modified Elixhauser score for predicting in-hospital mortality in internal medicine admissions
In-hospital mortality (IHM) is an indicator of the quality of care provided. The two most widely used scores for predicting IHM by International Classification of Diseases (ICD) codes are the... more
Comparison of late mortality after transcatheter aortic valve implantation versus surgical aortic valve replacement: Insights from a meta-analysis
Transcatheter aortic valve implantation (TAVI) has shown non-inferior late mortality in severe aortic stenosis (AS) patients in intermediate to inoperable risk for surgery compared to surgical aortic... more