Published: 5 January 2018
Author(s): M. Ruscica, C. Macchi, C. Pavanello, A. Corsini, A. Sahebkar, C.R. Sirtori
Issue: January 2018

Statins, the most widely used drugs in the Western world, have become a pivotal component in the primary and secondary prevention of vascular diseases. Although benefits have been well documented in younger-than-75-year-old individuals, the value of statins in people aged >75years and over is controversial. The CTT meta-analysis calculated an absolute risk reduction of 0.6%/year per 38.7mg/dl reduction in LDL-C levels in patients aged >75years, that would translate into a number needed to treat of 167.

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