Prediabetes is an intermediate metabolic state between normal glucose metabolism and diabetes mellitus. Patients with prediabetes have an increased risk (of up to 70%) of developing type 2 diabetes. Prediabetes is highly prevalent in patient with macrovascular disease including coronary artery disease, stroke and peripheral artery disease, persisting in the post-acute phase, which suggests true disturbance of glucose metabolism rather than a temporary reflection of stress. Moreover, the clinical and functional outcome in these patients is worse compared to patients with normal glucose metabolism.
