We read with interest the paper by Armiñanzasa et al., recently published in the European Journal of Internal Medicine [1]. The authors provided an important analysis of a large, prospectively collected, cohort of patients with possible/definite infective endocarditis enrolled in the Spanish Collaboration on Endocarditis—Grupo de Apoyo al Manejo de la Endocarditis infecciosa en España (GAMES) registry maintained by 39 Spanish hospitals from January 2008 to April 2015. According to this analysis an age ≥ 80 years, a Charlson Comorbidity Index score ≥ 3, and absence of surgical reparation, were independent predictors of mortality.
