Published: 5 May 2022
Author(s): Shay Perek, Alaa Khatib, Niv Izhaki, Ali Sleman Khalaila, Benjamin Brenner, Netanel A. Horowitz
Issue: July 2022
Section: Original article

Venous thromboembolism (VTE) is a major cause of morbidity and mortality in cancer patients. In a large population-based cohort study from Denmark, the VTE incidence within the first 6 months after cancer diagnosis has been shown to significantly increase between 1997 and 2017 [1]. Acute leukemias are prothrombotic diseases, which is attributed to the induction of leukemic cell procoagulant activity, especially following treatment-mediated leukemia cell death [2,3]. Catheter-related thrombosis (CRT), defined as VTE associated with central venous catheters (CVCs), may occur shortly after catheter insertion [4] and its incidence varies between 3.0 and 11.7%, depending on the leukemia subtype [5,6].


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