Primary biliary cholangitis (PBC), which was formerly called primary biliary cirrhosis, is a rare chronic immune-mediated liver disease [1,2]. A recent meta-analysis indicated that the pooled global incidence and prevalence of PBC were 1.76 and 14.60 per 100 000 persons, respectively, with clear regional and temporal differences [3]. Approximately 90 % of patients are female [4], mostly diagnosed between 50 and 60 years of age [1,5].The disease is histologically characterized by a non-suppurative destructive cholangitis of the small intrahepatic bile ducts [6].
