Atherosclerotic renal artery stenosis (ARAS) is a secondary cause of hypertension, with prevalence ranging from 1% to 5% in hypertensive patients. ARAS is associated with ischemic nephropathy, congestive heart failure and accelerated cardiovascular disease [1]. Autonomic dysfunction is a renowned risk factor for cardiovascular disease and several studies have documented that inflammation could play a crucial role between autonomic system and atherosclerosis [2]. The aim of the study is to evaluate if markers of increased cardiovascular risk, as autonomic dysfunction and QTc interval prolongation, can be detected in ARAS patients.