Published: 19 November 2022
Author(s): Chen Wang, Yiyun Shi
Issue: March 2023
Section: Letter to the Editor

Good syndrome is a rare adult-onset immunodeficiency syndrome, typically characterized by thymoma and hypogammaglobulinemia. Its clinical manifestations are highly variable, and concurrent non-infectious organ involvements secondary to immune dysregulation have been increasingly recognized, such as myasthenia gravis and immune-mediated cytopenias [1]. Among them, gastrointestinal manifestations resembling inflammatory bowel diseases or celiac disease were only described in case reports or small series; however, their clinical features, endoscopic and histologic findings remain largely undefined, and the optimal treatment as well as long-term outcomes are also not established given the rarity.


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