The ankle-brachial index (ABI) represents a dependable approach to the early detection of lower extremity peripheral arterial disease, rendering it a valuable vascular marker for cardiovascular (CV) disease assessment [1–3]. In the context of using ABI as an atherosclerosis indicator to evaluate CV risk, the selection of the lower ABI from either the left or right side is recommended [1–3]. Both bilateral and unilateral low ABI are currently categorized under the same label, namely low ABI. However, it is plausible that individuals with bilateral low ABI face a greater risk of CV disease than those with unilateral low ABI.