In the mid-2010s, after four decades of consistent decline, the mortality rate from heart disease began to show an increasing trend. This shift was largely attributed to the growing obesity epidemic [1]. Obesity constitutes a significant, multifaceted risk factor for atherosclerotic cardiovascular disease (ASCVD), directly influencing development of atherosclerosis through various mechanisms such as, increased blood pressure, endothelial dysfunction and vascular remodeling, while also serving as a primary risk factor for diabetes, hypertension, dyslipidemia, and chronic kidney disease, all predisposing factors for ASCVD, as well [2,3].
