Published: 21 May 2019
Author(s): Sabino Russi, Alessandra Vincenti, Angela Vinella, Maria Addolorata Mariggiò, Fabio Pavone, Franco Dammacco, Gianfranco Lauletta
Issue: May 2019
Section: Original Article

The role of CD5+ B cells in patients with HCV infection and HCV-related disorders, including mixed cryoglobulinemia (MC), has been addressed in previous reports with conflicting results. We established a correlation between CD5/CD20 expression on circulating B lymphocytes, characterizing monoclonal B cell lymphocytosis (MBL), and clinical features in a cohort of 45 patients with chronic HCV hepatitis [without MC: 23 patients (MC- group); with MC: 22 patients (MC+ group)], and 45 HCV-negative healthy subjects as controls.

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