May 2020
8 ArticlesCommentary
Tocilizumab for severe COVID-19: a promising intervention affecting inflammation and coagulation
The COVID-19 pandemic is causing significant morbidity and mortality worldwide. Although most patients experience predominantly a respiratory tract infection, a proportion of patients progresses to a... more
Internal Medicine Flashcard
Multiple cutaneous lesions and pulmonary cysts
A 50-year-old woman presented with multiple cutaneous lesions that had been present for many years (Figure 1a and 1b) similar to other family members. Her past history was significant for... more
A YOUNG LADY WITH CHEST PAIN
28-year-old woman with no significant past medical history presented with acute onset of sub-sternal chest pain at work. It was “pinching” type and got worse on deep breathing, coughing, leaning... more
Multiple facial prominences of benign origin
An 18-year-old girl sought medical advice for an asymptomatic prominence of the right malar region evolving for two years because of cosmetic concern. Her medical history was relevant for Salmonella... more
Internal Medicine Flashcards
Woman with sore throat, fever and abdominal pain
A 32-year-old woman, presented to the Emergency Department (ED) with a 15-day fever, and a sore throat recently associated with a growing abdominal pain. At admission in the ED, the patient had... more
Original Article
Efficacy and safety of tocilizumab in severe COVID-19 patients: a single-centre retrospective cohort study
Starting from December 2019, the World has faced a global pandemic of a novel coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [1]. As... more
Off-label use of tocilizumab for the treatment of SARS-CoV-2 pneumonia in Milan, Italy
Figure 4 modified: A curves showing survival of participants with severe COVID-19 pneumonia treated with tocilizumab: B. Kaplan-meier survival curves in patients with severe COVID-19 stratified... more
Impact of low dose tocilizumab on mortality rate in patients with COVID-19 related pneumonia
The epidemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) originating in Wuhan has dramatically spread in Italy, with very high mortality rates (7960 deaths over 46065 positive... more