Cannabis is the most used illicit drug. There is a worldwide trend to legalize cannabis, therefore, it is important to better understand the health impacts associated with its regular use. Recent studies have suggested that cannabis use increases cardiovascular (CV) risks [1–4]. Nevertheless, these studies focused on limited populations leading to influence the impact of cannabis use on CV health [5,6] and few studies have examined sex differences in cannabis use [7,8]. The use of medical cannabis is growing rapidly [9], but we have limited knowledge regarding safety and efficacy in various indications [10].
