Published: 21 February 2023
Author(s): Davide Scalvini, Patrizia Cambieri, Annalisa Schiepatti, Stiliano Maimaris, Francesca Lusetti, Claudia Vattiato, Piero Marone, Laura Villani, Federico Biagi
Issue: May 2023
Section: Original article

Whipple's disease (WD) is a chronic systemic infection due to Tropheryma whipplei (T. whipplei), a Gram-positive rod-shaped bacterium widespread in the environment, characterized by severe malabsorption, seronegative migratory arthropathies, fever, lymphadenopathy and neurological involvement, potentially leading to a fatal outcome if left untreated [1,2].


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