Published: 5 February 2024
Author(s): Jose Pablo Miramontes-González, Andreea Catalina Cristea, Miriam Gabella Martín, María González Fernández, José Luis Pérez-Castrillón
Issue: May 2024
Section: Letter to the Editor

Fever of unknown origin (FUO) was traditionally characterized by a temperature exceeding 38.3 °C on at least three occasions over a period of at least three weeks, with no apparent cause despite one week of inpatient investigation [1]. It has been categorized into infectious, non-infectious inflammatory diseases, malignancies, and other miscellaneous disorders. In recent years, new definitions and diagnostic methods have been incorporated into clinical practice. Especially with the progress in genetic research, there is a growing recognition of cases linked to mutations in inflammasome proteins as a cause of FUO.


Stay informed on our latest news!


This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.