A 56-year-old-man, born in Laos, was hospitalized for weight loss to 9 kg in 3 months, asthenia, pruritus and a skin and nails changed color. He had no significant past medical history. He described a decreased appetite, bowel discomfort and diarrhea. Clinical examination discovered alopecia (Fig. 1A) with total loss of hair (pubis, armpits, etc.), melanodermia and severe onychopathy.