Coronavirus disease 2019 (COVID-19) has strongly impacted on worldwide healthcare systems with significant resources diverted to deal with this unforeseeable modern pandemic. Several reports have described an increased cardiovascular mortality during the COVID-19 pandemic due to direct [1,2] and indirect effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection [3–8]. COVID-19 may induce oxygen supply/demand imbalance, abnormal systemic inflammatory response, atherosclerotic plaque rupture, overactivation of the coagulation system, and platelet hyperreactivity [1,2].